The ESCMID Study Group for Infectious Diseases of the Brain (ESGIB) aims to bring together international experts on diagnostics, treatment, and pathophysiology of infections of the brain. To advance their mission, ESGIB is committed to:
Toward optimal moxifloxacin dosing in tuberculous meningitis: A translational physiologically based pharmacokinetic modeling approach.
Sun M, Lynch K, Mariager T, Bodilsen J, Nau R, van Wijk RC, Manson ML, de Lange ECM, Guo T. Eur J Pharm Sci. 2026 May 1;220:107478
Management of community-acquired brain abscess and intracranial empyema: a survey of UK neurosurgical centres.
Perea CT, Roy H, Hatcher J, de Saram S, Bodilsen J, Whitfield P, Singleton W, Wildman J, Kameda-Smith MM, Gil E. Eur J Clin Microbiol Infect Dis. 2026 May 4.
Community-acquired bacterial meningitis in adults in Denmark (2015-2023): a prospective, nationwide, population-based cohort study.
Nielsen H, Storgaard M, Larsen L, Hansen BR, Mens H, Petersen PT, Tetens MM, Andersen CØ, Grønholm Jepsen MP, Lüttichau HR, Wiese L, Brandt CT, Bodilsen J. Lancet Reg Health Eur. 2026 Feb 21;64:101628.
Clinical features and outcomes of Staphylococcus aureus brain abscess in Denmark and the Netherlands: a multicentre cohort study.
Eriksen EM, Bijlsma M, Olie S, Larsen L, Storgaard M, Mens H, Nielsen H, Brouwer M, Bodilsen J; DASGIB study group. Infect Dis (Lond). 2026 May;58(5):507-517
Infectious encephalitis among adults: a prospective and population-based cohort study.
Duerlund LS, Larsen L, Storgaard M, Mens H, Wiese L, Grønholm Jepsen MP, Hansen BR, Lüttichau HR, Andersen CØ, Blaabjerg M, Venkatesan A, Nielsen H, Bodilsen J; DASGIB study group. Clin Microbiol Infect. 2026 Apr 11:S1198-743X(26)00185-0
Early vs late diagnosis in infectious encephalitis: a population-based cohort study.
Duerlund LS, Larsen L, Storgaard M, Mens H, Wiese L, Grønholm Jepsen MP, Hansen BR, Lüttichau HR, Andersen CØ, Blaabjerg M, Venkatesan A, Nielsen H, Bodilsen J; DASGIB Study Group. Clin Microbiol Infect. 2026 Apr 16:S1198-743X(26)00193-X
Herpes simplex virus type 1 encephalitis: A prospective population-based cohort study.
Duerlund LS, Larsen L, Storgaard M, Mens H, Wiese L, Jepsen MPG, Hansen BR, Lüttichau HR, Andersen CØ, Blaabjerg M, Venkatesan A, Nielsen H, Bodilsen J; DASGIB study group. Clin Infect Dis. 2026 Feb 23:ciag
Re: 'Oral switch versus continued intravenous antibiotic therapy in patients with bacteraemia and sepsis' by Li et al.
Bodilsen J. Clin Microbiol Infect. 2025 Aug;31(8):1419-1420
Recurrent brain abscess after 18 years in an adult with undiagnosed congenital sinus venosus atrial septal defect.
Bergmann S, Nielsen ME, Nielsen HL, Bodilsen J. Clin Microbiol Infect. 2025 Nov;31(11):1928-1930
Optimization of antiviral dosing in Herpesviridae encephalitis: a promising approach to improve outcome?
Nau R, Seele J, Bodilsen J, Groß U. Clin Microbiol Infect. 2025 Apr;31(4):534-541
Clinical features and outcome of brain abscess after introduction of CT and MRI: A meta-analysis.
Bodilsen J, Eriksen EM, Nielsen MD, Duerlund LS, Mariager T, Nielsen H, Brouwer MC. J Infect. 2025 Feb;90(2):106394.
Heparin-Binding Protein in Cerebrospinal Fluid as a Biomarker for Bacterial Meningitis: A Study of Diagnostic Accuracy.
Olie SE, Staal SL, da Cruz Campos AC, Bodilsen J, Nielsen H, van de Beek D, Brouwer MC. Ann Neurol. 2025 Jun;97(6):1088-1095
Distribution of ganciclovir in the porcine central nervous system.
Guldbæk JM, Mariager T, Nielsen MD, Terkelsen JH, Nau R, Bjarkam CR, Nielsen H, Bodilsen J. Antimicrob Agents Chemother. 2025 May 7;69(5):e0181524
Ventriculitis characteristics and outcomes (VELCRO): an international retrospective cohort study.
Luque Paz D, Díaz-Pollán B, Boyer-Besseyre M, Djanikian F, Munier AL, Cunha F, Escaut L, Martin-Blondel G, Sarton B, Jaquet P, Arrivé F, Wolf R, Legros V, Willig M, Sipahi OR, Flurin L, Bianchi A, Balança B, Díez-Vidal A, Puel J, Soyer B, Lino R, Leveque T, Salomon A, Serris A, Larcher R, Bruneel F, Mongardon N, Martinot M, Mazeraud A, Wolff M, Sonneville R, Valour F, Tattevin P; ESGIB-SPILF-SFAR Research Network-VELCRO study group. Brain. 2025 May 20:awaf178
Distribution of acyclovir in central nervous system compartments: a porcine pharmacokinetic model.
Mariager T, Terkelsen JH, Guldbæk JM, Nielsen MD, Vestergaard J, Bue M, Öbrink-Hansen K, Nau R, Bjarkam CR, de Lange ECM, Nielsen H, Bodilsen J. Antimicrob Agents Chemother. 2025 Aug 6;69(8):e0181124
Validation and clinical implementation of cerebrospinal fluid C-reactive protein for the diagnosis of bacterial meningitis: a prospective diagnostic accuracy study.
Olie SE, Staal SL, Groeneveld NS, Schotman HHM, Bodilsen J, Nielsen H, Bijlsma MW, van de Beek D, Brouwer MC. Lancet Reg Health Eur. 2025 Apr 29;53:101309
Revisiting Acyclovir Dosing for Adult Viral Encephalitis Using a Full Bayesian LeiCNS PBPK Modeling Approach.
Sun M, Manson ML, Märtson AG, Bodilsen J, de Lange ECM, Guo T. Clin Pharmacokinet. 2025 Sep;64(9):1413-1423
European Society of Clinical Microbiology and Infectious Diseases guidelines on diagnosis and treatment of brain abscess in children and adults.
Bodilsen J, D'Alessandris QG, Humphreys H, Iro MA, Klein M, Last K, Montesinos IL, Pagliano P, Sipahi OR, San-Juan R, Tattevin P, Thurnher M, Rangel RJT, Brouwer MC; ESCMID Study Group for Infections of the Brain (ESGIB). Clin Microbiol Infect. 2024;30(1):66–89.
ChatGPT fails challenging the recent ESCMID brain abscess guideline.
Dyckhoff-Shen S, Koedel U, Brouwer MC, Bodilsen J, Klein M. J Neurol. 2024 Apr;271(4):2086-2101
Community-acquired Staphylococcus aureus meningitis in adults.
Van Soest TM, Søndermølle MB, Brouwer MC, Chekrouni N, Larsen AR, Petersen A, van Sorge NM, Nielsen H, van de Beek D, Bodilsen J; DASGIB study group. J Infect. 2023;86(3):239–244.
Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood-brain barrier function.
Teske NC, Dyckhoff-Shen S, Beckenbauer P, Jan Philipp Bewersdorf, Engelen-Lee JY, Hammerschmidt D,Kälin R, Pfister HW, Brouwer MC, Klein M, Glaß R, van de Beek D, Koedel U. J Neuroinflammation. 2023;20(1):267.
Progressive multifocal leukoencephalopathy treated by immune checkpoint inhibitors.
Boumaza X, Bonneau B, Roos-Weil D, Pinnetti C, Rauer S, Nitsch L, Del Bello A, Jelcic I, Sühs KW,Gasnault J, Goreci Y, Grauer O, Gnanapavan S, Wicklein R, Lambert N, Perpoint T, Beudel M, Clifford D, Sommet A, Cortese I, Martin-Blondel G, for the Immunotherapy for PMLStudy Group. Ann Neurol. 2023;93(2):257–270.
Encephalitis in travellers: a prospective multicentre study.
Picard L, Mailles A, Fillâtre P, Tattevin P, Stahl JP; ENCEIF scientific committee. J Travel Med. 2023;30(2):taac145.
Diagnosis and treatment of CNS infections
Post-graduate course
23 - 25 September 2026
Aalborg, Denmark
If you have questions or comments for our study group, we warmly invite you to contact us!
