The ESCMID Study Group for Infectious Diseases of the Brain (ESGIB) aims to bring together international experts on diagnostics, treatment, and pathophysiology of infections of the brain. To advance their mission, ESGIB is committed to:
Optimization of antiviral dosing in Herpesviridae encephalitis: a promising approach to improve outcome?
Nau R, Seele J, Bodilsen J, Groß U. Clin Microbiol Infect. 2025 Apr;31(4):534-541
Clinical features and outcome of brain abscess after introduction of CT and MRI: A meta-analysis.
Bodilsen J, Eriksen EM, Nielsen MD, Duerlund LS, Mariager T, Nielsen H, Brouwer MC. J Infect. 2025 Feb;90(2):106394.
Heparin-Binding Protein in Cerebrospinal Fluid as a Biomarker for Bacterial Meningitis: A Study of Diagnostic Accuracy.
Olie SE, Staal SL, da Cruz Campos AC, Bodilsen J, Nielsen H, van de Beek D, Brouwer MC. Ann Neurol. 2025 Jun;97(6):1088-1095
Distribution of ganciclovir in the porcine central nervous system.
Guldbæk JM, Mariager T, Nielsen MD, Terkelsen JH, Nau R, Bjarkam CR, Nielsen H, Bodilsen J. Antimicrob Agents Chemother. 2025 May 7;69(5):e0181524
Ventriculitis characteristics and outcomes (VELCRO): an international retrospective cohort study.
Luque Paz D, Díaz-Pollán B, Boyer-Besseyre M, Djanikian F, Munier AL, Cunha F, Escaut L, Martin-Blondel G, Sarton B, Jaquet P, Arrivé F, Wolf R, Legros V, Willig M, Sipahi OR, Flurin L, Bianchi A, Balança B, Díez-Vidal A, Puel J, Soyer B, Lino R, Leveque T, Salomon A, Serris A, Larcher R, Bruneel F, Mongardon N, Martinot M, Mazeraud A, Wolff M, Sonneville R, Valour F, Tattevin P; ESGIB-SPILF-SFAR Research Network-VELCRO study group. Brain. 2025 May 20:awaf178
Distribution of acyclovir in central nervous system compartments: a porcine pharmacokinetic model.
Mariager T, Terkelsen JH, Guldbæk JM, Nielsen MD, Vestergaard J, Bue M, Öbrink-Hansen K, Nau R, Bjarkam CR, de Lange ECM, Nielsen H, Bodilsen J. Antimicrob Agents Chemother. 2025 Aug 6;69(8):e0181124
Validation and clinical implementation of cerebrospinal fluid C-reactive protein for the diagnosis of bacterial meningitis: a prospective diagnostic accuracy study.
Olie SE, Staal SL, Groeneveld NS, Schotman HHM, Bodilsen J, Nielsen H, Bijlsma MW, van de Beek D, Brouwer MC. Lancet Reg Health Eur. 2025 Apr 29;53:101309
Revisiting Acyclovir Dosing for Adult Viral Encephalitis Using a Full Bayesian LeiCNS PBPK Modeling Approach.
Sun M, Manson ML, Märtson AG, Bodilsen J, de Lange ECM, Guo T. Clin Pharmacokinet. 2025 Sep;64(9):1413-1423
European Society of Clinical Microbiology and Infectious Diseases guidelines on diagnosis and treatment of brain abscess in children and adults.
Bodilsen J, D'Alessandris QG, Humphreys H, Iro MA, Klein M, Last K, Montesinos IL, Pagliano P, Sipahi OR, San-Juan R, Tattevin P, Thurnher M, Rangel RJT, Brouwer MC; ESCMID Study Group for Infections of the Brain (ESGIB). Clin Microbiol Infect. 2024;30(1):66–89.
ChatGPT fails challenging the recent ESCMID brain abscess guideline.
Dyckhoff-Shen S, Koedel U, Brouwer MC, Bodilsen J, Klein M. J Neurol. 2024 Apr;271(4):2086-2101
Community-acquired Staphylococcus aureus meningitis in adults.
Van Soest TM, Søndermølle MB, Brouwer MC, Chekrouni N, Larsen AR, Petersen A, van Sorge NM, Nielsen H, van de Beek D, Bodilsen J; DASGIB study group. J Infect. 2023;86(3):239–244.
Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood-brain barrier function.
Teske NC, Dyckhoff-Shen S, Beckenbauer P, Jan Philipp Bewersdorf, Engelen-Lee JY, Hammerschmidt D,Kälin R, Pfister HW, Brouwer MC, Klein M, Glaß R, van de Beek D, Koedel U. J Neuroinflammation. 2023;20(1):267.
Progressive multifocal leukoencephalopathy treated by immune checkpoint inhibitors.
Boumaza X, Bonneau B, Roos-Weil D, Pinnetti C, Rauer S, Nitsch L, Del Bello A, Jelcic I, Sühs KW,Gasnault J, Goreci Y, Grauer O, Gnanapavan S, Wicklein R, Lambert N, Perpoint T, Beudel M, Clifford D, Sommet A, Cortese I, Martin-Blondel G, for the Immunotherapy for PMLStudy Group. Ann Neurol. 2023;93(2):257–270.
Encephalitis in travellers: a prospective multicentre study.
Picard L, Mailles A, Fillâtre P, Tattevin P, Stahl JP; ENCEIF scientific committee. J Travel Med. 2023;30(2):taac145.
CNS infections in resource-limited setting: Tetanus and eosinophilic meningitis
29 January 2026 at 16:00 CET
Tuberculous meningitis; new guideline, new trial data and use of anti-inflammatory therapy
16 October 2025 at 14:00 CET
Host versus pathogen in bacterial meningitis: The titanic battle between bacteria and the brain in animal models and patients
25 June 2025 at 15:00 CET
If you have questions or comments for our study group, we warmly invite you to contact us!
Registration for ESCMID Global 2026 in Munich is now open.
Register now to get the early registration fee and attend the world’s most eminent event in the field of infection.