A rapidly expanding Bundibugyo virus outbreak spans five Democratic Republic of the Congo provinces and Uganda, reaching 1,759 cases in the DRC, complicated by healthcare worker infections and an exported case to France. Mpox activity is intensifying across Africa, with clade Ib cases in Madagascar doubling to over 4,000 and Guinea-Bissau reporting its first confirmed case. Global measles resurgence continues, marked by 883 cases and three deaths in England, 121 cases threatening elimination status in the Maldives, and 14,470 suspected cases with 87 child deaths in Yemen. Aedes-borne arboviruses are surging, with dengue expanding in Singapore, Mexico, and the Dominican Republic, while chikungunya has re-emerged in Costa Rica and the Philippines. Elsewhere, Palestine reported over 9,000 varicella cases amid displacement, and a multi-country European salmonellosis outbreak linked to alfalfa sprouts caused 109 cases.
Measles — Europe
Measles: Reports this week highlight continued global measles resurgence, with major signals from the UK, Maldives, and Yemen. England reported 883 confirmed cases and three deaths, underscoring renewed transmission in Europe. The Maldives recorded 121 cases, threatening its elimination status, while Yemen reported 14,470 suspected cases and 87 child deaths, reflecting severe impact in a fragile health-system setting.
Dengue — North America
Aedes-borne arboviral activity is intensifying across Asia and the Americas with the seasonal peak. Dengue is expanding in Singapore (135 cases, three Seletar "red zones"), Acapulco, Mexico (DENV-2 co-circulating with the predominant DENV-3, raising severity risk), and the Dominican Republic (153 cases, exceeding the 2015 total). Chikungunya has re-emerged in immunologically naïve populations — Playa Langosta, Costa Rica (first circulation since 2017) and two villages in Samar, Philippines, under "Code Red" with 84 cases.
Ebola virus disease — Africa
An outbreak of Bundibugyo virus continues spreading rapidly across five DRC provinces and Uganda, reaching 1759 cases in the DRC by 9 July 2026. Recent expansion includes possible local transmission in Kisangani and an exported case in a healthcare worker returning to France. Containment is challenged by a lack of approved vaccines, community resistance, and healthcare worker infections, though a clinical trial has opened and Uganda has approved galidesivir for compassionate use.
Mpox — Africa
Mpox activity is intensifying and shifting in Africa. In Madagascar, the clade Ib outbreak has roughly doubled — from about 2,000 to over 4,000 confirmed cases (15 deaths) across 39 districts in two weeks — with continued geographic expansion, including an eastward shift beyond the original Mahajanga cluster. Meanwhile, Guinea-Bissau has reported its first-ever confirmed case, clade differentiation still pending; as an initial detection it may represent the tip of the iceberg, signalling possible wider undetected spread.
883 confirmed cases and three deaths reported in 2026, with most cases in London.
121 confirmed cases reported in an outbreak threatening the nation's elimination status.
Sustained transmission with 14,470 suspected cases and 87 child deaths in government-controlled areas.
300 probable and 26 confirmed cases reported, with serotypes 2 and 3 circulating.
135 confirmed cases in Yio Chu Kang, with three red zones identified in Seletar.
153 confirmed cases and zero deaths reported as of June 27, predominantly affecting males.
Epidemic zones declared in Rayong and Bangkok-Samut Prakan amid elevated rural and urban transmission.
Over 9000 cases reported within two weeks amid mass displacement and overcrowding
Fatalities reported in Tokat and Sivas provinces during the peak tick season.
109 cases, 18 hospitalizations, and two deaths linked to contaminated alfalfa sprouts.
1,251 cases reported in Michigan, with hundreds more confirmed across several other states.
400 cases reported year-to-date in the southeastern region, nearly four times the 2025 total.
Localised outbreak in Playa Langosta with four confirmed and 17 probable cases reported.
National cases exceed 6000 amid an El Niño-related State of Emergency and heavy rainfall.
84 confirmed cases reported in two villages in Gandara municipality, prompting a Code Red.
First confirmed cases of 2026 reported in Ulsan and Jeonnam-Gwangju during peak transmission season
1759 cases reported amid rapid spread to new provinces and exported cases to France.
First confirmed case reported, with viral clade differentiation currently pending.
Sustained clade Ib transmission reported, reaching 4117 cases and 15 deaths across 39 districts.
The ESCMID-AUMC Epi Alert, a strategic collaboration between the ESCMID Emerging Infections Subcommittee and the Center of Tropical Medicine and Travel Medicine of Amsterdam University Medical Center (AUMC) that integrates expertise and resources to advance emerging infectious diseases surveillance and intelligence sharing. This collaboration integrates ESCMID's extensive international network and emerging infections expertise with AUMC's proven surveillance capabilities, led by Dr. Abraham Goorhuis and the AUMC team and other collaborators form European Institutions.
The Epi Alert aims to be a weekly publication. The briefings are curated by infectious disease specialists prioritising data from trusted sources (such as Beacon, H-Radar, Outbreaknews, WHO, ECDC, CDC) based on potential impact, geographic region and urgency/relevancy to clinical practice. It aims to provide concise summaries for busy healthcare professionals with direct links for further investigation and transparency.
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