Aims and objectives

The ESCMID PK/PD of Anti-Infectives Study Group (EPASG) is dedicated to advancing the exploration and progression of pharmacodynamics and pharmacokinetics (PK/PD), as well as the dosing of anti-infectives. Its mission extends to innovative research on resistance development and paves the way for the development of ground-breaking antibiotics. As a European platform uniting scientists and healthcare providers actively engaged in these critical fields, EPASG is committed to: 

  • Raising awareness on the critical role of exposure/effect relationships, advocating for optimal dosing strategies that ensure efficacy, safety, clinical outcomes, and resistance prevention
  • Providing training and inspiration to scientists, physicians, and related groups through dynamic conferences, educational workshops, special symposia, and publications 
  • Offering guidance and fostering knowledge among European countries, other ESCMID study groups, international societies, regulatory agencies, and government authorities

Activities and resources

EPASG Newsletter, November 2025

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EPASG Newsletter, April 2025

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related: template session proposals for 2026

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The pharmacokinetics of antibiotics in patients with obesity: a systematic review and consensus guidelines for dose adjustments. 

Märtson AG, Barber KE, Crass RL, Hites M, Kloft C, Kuti JL, Nielsen EI, Pai MP, Zeitlinger M, Roberts JA, Tängdén T; Pharmacokinetics and Pharmacodynamics of Anti-Infectives Study Group of the European Society of Clinical Microbiology and Infectious Diseases, the International Society of Anti-Infective Pharmacology, and the Society of Infectious Diseases Pharmacists. Lancet Infect Dis. 2025 Sep;25(9):e504-e515

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An easy-to-use predictive score for identifying patients at risk of suboptimal linezolid exposure and candidates for therapeutic drug monitoring. 

Fresán D, Sorlí L, Barceló-Vidal J, Rodrigo-Moreno A, Muñoz R, Subirana I, Ferrer A, Velasco C, Roberts J, Benítez-Cano A, Luque S; PK/PD of Anti-Infectives Study Group of the European Society of Clinical Microbiology and Infectious Diseases (EPASG). Int J Antimicrob Agents. 2025 Nov 4;67(1):107661

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Towards model-informed precision dosing of intravenous linezolid: a multicentre external evaluation of pharmacokinetic models in critically ill adults. 

Starp J, Leonhardt A, Zoller M, Scharf C, Zander J, Paal M, Greppmair S, Schatz LM, Ermtraud J, Kunzelmann AK, König C, Grensemann J, Reiter L, Lau C, Marriott D, Stocker SL, Wicha SG, Liebchen U; PK/PD Study Group of the European Society of Clinical Microbiology and Infectious Diseases (EPASG). Clin Microbiol Infect. 2025 Sep 9:S1198-743X(25)00447-1

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International consensus recommendations for the use of prolonged-infusion beta-lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists 

Hong LT, Downes KJ, FakhriRavari A, Abdul-Mutakabbir JC, Kuti JL, Jorgensen S, Young DC, Alshaer MH, Bassetti M, Bonomo RA, Gilchrist M, Jang SM, Lodise T, Roberts JA, Tängdén T, Zuppa A, Scheetz MH. Pharmacotherapy. 2023;43(8):740–777.

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Precision Antimicrobial Therapy in Sepsis — PK/PD, Timing, and TDM

19 November 2025 at 14:00 CET

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My case where PK/PD made the difference!

24 June 2025 at 14:00 CET

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Controversies in TDM of antifungals

17 February 2025, 17:30-18:30 CET

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Toxicity of antimicrobials

27 March 2024

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How to write successful grant applications – Insights from successful applicants and reviewers 

19 September 2023

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Phage pharmacology and therapy

4 December 2023

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Executive Committee

  Sebastian Wicha

Sebastian Wicha

Chair
Universtät Hamburg, Institute of Pharmacy
Hamburg, Germany
  Cornelia Landersdorfer

Cornelia Landersdorfer

Education Officer
Monash University
Parkville, Australia
  Birgit Koch

Birgit Koch

Science Officer
Erasmus MC, Hospital pharmacy
Rotterdam, Netherlands
  Markus Zeitlinger

Markus Zeitlinger

Secretary
Medical University of Vienna, Clinical Pharmacology
Vienna, Austria
  Sonia Luque

Sonia Luque

Treasurer
Hospital del Mar, Pharmacy department
Barcelona, Spain
  Iris Minichmayr

Iris Minichmayr

Ad hoc: Social Media
Medical University Vienna
Vienna, Austria
  Anne-Grete Märtson

Anne-Grete Märtson

Ad hoc: Social Media
Leiden Academic Centre for Drug Research (LACDR)
Leiden, Netherlands

Contact

If you have questions or comments for our study group, we warmly invite you to contact us!

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