The ESCMID PK/PD of Anti-Infectives Study Group (EPASG) is dedicated to advancing the exploration and progression of pharmacodynamics and pharmacokinetics (PK/PD), as well as the dosing of anti-infectives. Its mission extends to innovative research on resistance development and paves the way for the development of ground-breaking antibiotics. As a European platform uniting scientists and healthcare providers actively engaged in these critical fields, EPASG is committed to:
The pharmacokinetics of antibiotics in patients with obesity: a systematic review and consensus guidelines for dose adjustments.
Märtson AG, Barber KE, Crass RL, Hites M, Kloft C, Kuti JL, Nielsen EI, Pai MP, Zeitlinger M, Roberts JA, Tängdén T; Pharmacokinetics and Pharmacodynamics of Anti-Infectives Study Group of the European Society of Clinical Microbiology and Infectious Diseases, the International Society of Anti-Infective Pharmacology, and the Society of Infectious Diseases Pharmacists. Lancet Infect Dis. 2025 Sep;25(9):e504-e515
An easy-to-use predictive score for identifying patients at risk of suboptimal linezolid exposure and candidates for therapeutic drug monitoring.
Fresán D, Sorlí L, Barceló-Vidal J, Rodrigo-Moreno A, Muñoz R, Subirana I, Ferrer A, Velasco C, Roberts J, Benítez-Cano A, Luque S; PK/PD of Anti-Infectives Study Group of the European Society of Clinical Microbiology and Infectious Diseases (EPASG). Int J Antimicrob Agents. 2025 Nov 4;67(1):107661
Towards model-informed precision dosing of intravenous linezolid: a multicentre external evaluation of pharmacokinetic models in critically ill adults.
Starp J, Leonhardt A, Zoller M, Scharf C, Zander J, Paal M, Greppmair S, Schatz LM, Ermtraud J, Kunzelmann AK, König C, Grensemann J, Reiter L, Lau C, Marriott D, Stocker SL, Wicha SG, Liebchen U; PK/PD Study Group of the European Society of Clinical Microbiology and Infectious Diseases (EPASG). Clin Microbiol Infect. 2025 Sep 9:S1198-743X(25)00447-1
International consensus recommendations for the use of prolonged-infusion beta-lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists
Hong LT, Downes KJ, FakhriRavari A, Abdul-Mutakabbir JC, Kuti JL, Jorgensen S, Young DC, Alshaer MH, Bassetti M, Bonomo RA, Gilchrist M, Jang SM, Lodise T, Roberts JA, Tängdén T, Zuppa A, Scheetz MH. Pharmacotherapy. 2023;43(8):740–777.
If you have questions or comments for our study group, we warmly invite you to contact us!
