Research & Projects

ESCMID Panorama

Presentations & Publications

2016

5 May 2016 mBio vol. 7 no. 3 e00444-16; doi: 10.1128/mBio.00444-16

 

In this ESGEM paper, we combined WGS data from 308 invasive Staphylococcus aureus isolates corresponding to a pan-European population snapshot, with epidemiological and resistance data. We argue that this work provides a comprehensive road map illustrating the three vital components for future molecular epidemiological surveillance: (i) large-scale structured surveys, (ii) WGS, and (iii) community-oriented database infrastructure and analysis tools.

2013 and before

ESGEM articles in special Eurosurveillance issue

ESGEM published three articles in a special Eurosurveillance issue on the molecular epidemiology of human pathogens (part two) presenting several reviews on advantages and challenges of available molecular methods
Eurosurveillance, Volume 18, Issue 4, 24 January 2013

Overview of molecular typing methods for outbreak detection and epidemiological surveillance. AJ Sabat, A Budimir, D Nashev, R Sá-Leão, JM van Dijl, F Laurent, H Grundmann, AW Friedrich, on behalf of the ESCMID Study Group of Epidemiological Markers (ESGEM)
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Bioinformatics in bacterial molecular epidemiology and public health: databases, tools and the next-generation sequencing revolution. JA Carriço, AJ Sabat, AW Friedrich, M Ramirez, on behalf of the ESCMID Study Group for Epidemiological Markers (ESGEM)
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From Theory to Practice: Molecular Strain Typing for the Clinical and Public Health Setting. RV Goering, R Köck, H Grundmann, G Werner, AW Friedrich, on behalf of the ESCMID Study Group for Epidemiological Markers (ESGEM)
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Geographic distribution of Staphylococcus aureus causing invasive infections in Europe: a molecular-epidemiological analysis.

Grundmann H, Aanensen DM, van den Wijngaard CC, Spratt BG, Harmsen D, Friedrich AW; European Staphylococcal Reference Laboratory Working Group.
PLoS Med. 2010 Jan 12;7(1):e1000215.

Guidelines for the validation and application of typing methods for use in bacterial epidemiology

van Belkum A, Tassios P, Dijkshoorn L, Haeggman S, Cookson B, Fry NK, Fussing V, Green J, Feil E, Gerner-Smidt P, Brisse S, and Struelens M for the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group on Epidemiological Markers (ESGEM).
Clinical Microbiology and Infection 2007; 13 (Suppl 3), 1-46.

ESCMID Medical Guidelines

Current trends in the epidemiological typing of clinically relevant microbes in Europe

Maquelin K, Cookson B, Tassios P, van Belkum A; for the European Society for Microbiology and Infectious Diseases (ESCMID) Study Group on Epidemiological Markers (ESGEM). J Microbiol Methods. 2007 Apr;69(1):222-6.

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Harmonization of pulsed-field gel electrophoresis protocols for epidemiological typing of strains of methicillin-resistant Staphylococcus aureus: a single approach developed by consensus in 10 European laboratories and its application for tracing the spre

Stephen Murchan, Mary Elizabeth Kaufmann, Ariane Deplano, Raf de Ryck, Marc Struelens, Christina Elsberg Zinn, Vivian Fussing, Saara Salmenlinna, Jaana Vuopio-Varkila, N_vine El Solh, Christina Cuny, Wolfgang Witte, Panayotis T. Tassios, Nikolas Legakis, Willem van Leeuwen, Alex van Belkum, Anna Vindel, Idoia Laconcha, Javier Garaizar, Saara Haeggman, Barbro Olsson-Liljequist, Ulrika Ransjo, Geoffrey Coombes, and Barry Cookson.
J. Clin. Microbiol. 2003, 41: 1574-1585.

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Biologists deploy database to quash drug-resistant bacteria

Comment in Nature, 24 April 2003: Tom Clarke. Nature 422:791

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Molecular typing of methicillin-resistant Staphylococcus aureus by pulsed-field gel electrophoresis: comparison of results obtained in a multilaboratory effort using identical protocols and MRSA strains.

Chung M, de Lencastre H, Matthews P, Tomasz A, and the Multilaboratory Project Collaborators – Adamsson I, Aires de Sousa M, Camou T, Cocuzza C, Corso A, Couto I, Dominguez A, Gniadkowski M, Goering R, Gomes A, Kikuchi K, Marchese A, Mato R, Melter O, Oliveira D, Palacio R, Sa-Leao R, Santos Sanches I, Song J-H, Tassios PT, Villari P.
Microb Drug Res 2000, 6: 189-198.

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Multicenter evaluation of epidemiological typing of methicillin-resistant Staphylococcus aureus strains by repetitive-element PCR analysis. The European Study Group on Epidemiological Markers of the ESCMID

Deplano A, Schuermans A, Van Eldere J, et al.
Journal of Clinical Microbiology 2000; 38: 3527-3533.

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A multicenter evaluation of genotypic methods for the epidemiologic typing of Legionella pneumophila serogroup 1: results of a pan-European study

Fry NK, Alexiou-Daniel S, Bangsborg JM, et al.
Clinical Microbiology and Infection 1999; 5: 462-477.

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Assessment of resolution and intercenter reproducibility of results of genotyping Staphylococcus aureus by pulsed-field gel electrophoresis of SmaI macrorestriction fragments: a multicenter study

Van Belkum A, Van Leeuwen W, Kaufmann ME, et al.
Journal of Clinical Microbiology 1998; 36: 1653-1659.

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Multicenter study using standardized protocols and reagents for evaluation of reproducibility of PCR-based fingerprinting of Acinetobacter spp.

Grundmann HJ, Towner KJ, Dijkshoorn L, et al.
Journal of Clinical Microbiology 1997; 35: 3071-3077.

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Consensus guidelines for appropriate use and evaluation of microbial epidemiologic typing systems

Struelens MJ and the Members of the European Study Group on Epidemiological Markers (ESGEM) of the European Society for Clinical Microbiology and Infectious Diseases (ESCMID).
Clinical Microbiology and Infection 1996; 2: 2-11.

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Last update: 16 June 2016