Research & Projects

ESCMID Panorama

ESCMID initiatives

Fighting Antimicrobial Resistance is a core activity within ESCMID. Here you can get an overview on larger ESCMID Initiatives in this field.

News on ESCMID's AMR activities

At the occasion of World Antibiotic Awareness Week from 13 19 November and European Antibiotic Awareness Day 18 November several players within the ESCMID network organize a number of activities to promote prudent use of antibiotics in Europe. They include events at healthcare institutions and public campaigns on antimicrobial resistance (AMR), surveillance and antibiotic stewardship programmes.

The European Committee for Infection Control (EUCIC) is organizing a training module for an Infection Prevention and Control Certificate, which aims to provide a unique European perspective on infection prevention and control. It does this by sharing the expertise and competencies within training centres, countries and professions. This collaborative effort will result in the training of a new generation of IPC specialists. For more information, please refer to EUCIC training programme website, where you can find the flyer and details about the current training programme.

ESCMID’s study group for antimicrobial stewardship, ESGAP, together with the Turkish Society of Clinical Microbiology and Infectious Diseases, KLIMIK, organized a postgraduate course on antimicrobial policies. Intersectoral residents and specialists interested in antimicrobial stewardship will get an overview of antimicrobial resistance, consumption surveillance as well as the implementation and integration of antimicrobial stewardship strategies and programmes.

Several ESCMID representatives contributed to a new report published by WHO, which found very few potential treatment options for the most threatening antibiotic-resistant infections. The core report is complemented by an updated document describing their priority pathogen list.

The American Society for Microbiology (ASM) and ESCMID organized a multidisciplinary meeting to address the challenges, opportunities and current requirements for antimicrobial drug development to tackle antimicrobial drug resistance. The presentations from the conference, which took place from 6 - 8 September 2017 in Boston, are available in ESCMID’s eLibrary now.

Members of EPI-NET, COMBACTE-NET and the EUCIC group for SUSPIRE published a systematic review, which evaluated healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) indicators of 56 surveillance systems in 20 countries across Europe. Of these surveillance systems, 33 (58.9%) targeted HAIs, 45 (80.3%) AMR and 22 targeted both. The most frequent indicator of AMR was the proportion of resistant isolates (27/34 providing information; 79.42%); incidence rates were included in 18 (52.9%) systems. For HAIs in ICUs, 22 (100%) systems included data on central line-associated bloodstream infections, 19 (86.3%) included information on ventilator-associated pneumonia and catheter-associated urinary tract infections. Incidence density was the most frequent indicator in these types of infections. Regarding surgical site infections, the most frequent procedures included were hip prosthesis, colon surgery and caesarean section (21/22 systems; 95.5% of the systems). The authors conclude that publicly available information about the methods and indicators of surveillance systems is still frequently lacking and that there is a wide heterogeneity in procedures and indicators reported.

An ESGAP expert commentary in Clinical Microbiology and Infection discussed the urgent need to plan and fund teams of specialist health workers to promote appropriate antibiotics use. Ideally, such teams should consist of ID specialists, microbiologists, nurses and pharmacists. Together, their collaborative effort can improve diagnosis and treatment of infections as well as prevent the rise of drug-resistant bacteria. 

Link to the full press release  and the expert opinion piece

At the occasion of World Antibiotic Awareness Week from 14 - 20 November and European Antibiotic Awareness Day 18 November the European Committee on Infection Control (EUCIC) and the ESCMID Study Group for Antibiotic Policies (ESGAP) organize a number of activities to promote prudent use of antibiotics in Europe. They include events at healthcare institutions and public campaigns on antimicrobial resistance (AMR), surveillance and antibiotic stewardship programmes in Moldova, Turkey, Spain, Cyprus and the Netherlands.

The ESCMID/ASM Conference on Drug Development to Meet the Challenge of Antimicrobial Resistance has come to a close in Vienna, Austria. The conference addressed issues such as the reliance on very robust preclinical studies, innovative clinical trial design, strong academic-industrial partnerships, and a requirement for early engagement with regulatory bodies in order to facilitate the processes for accelerated antimicrobial development. You may find more information on the presentations in the ESCMID eLibrary and a press release summarizing the highlights.

During the current UN General Assembly, a high-level meeting on antimicrobial resistance (AMR) is scheduled on 21 September 2016. As one of the most experienced players in this specialized field, ESCMID urges the UN to focus on concrete outcomes from this high-level meeting. Measures to effectively fight AMR should include improving surveillance of resistance, regulation of the appropriate use of antimicrobial drugs in human medicine and animal farming, education and public campaigns on overuse as well as incentives and funding systems to promote the development of new medicines, new diagnostics and innovative interventions to improve antibiotic use and infection control. We look forward to the outcomes and strongly support the work of the WHO, FAO and the OIE.

We aim to explore current practices regarding durations of antibiotic treatments in common infections, in order to get an international picture on the topic. The duration of antibiotic therapy is indeed not completely solved for many infectious syndromes. The survey is intended for senior or trainee specialists in infectious diseases or clinical microbiology, clinical pharmacists, or any healthcare professional part of an antimicrobial stewardship team worldwide, provided that these professionals regularly give advice on antibiotic prescriptions (outside their own department).
The questionnaire will take around 5-7 minutes and is strictly anonymous. Click here to go to the survey and complete before the end of November 2016.

The European Committee on Antimicrobial Susceptibility Testing (EUCAST) published five instruction videos on how to perform antimicrobial susceptibility testing (AST) using EUCAST recommended methods and interpretation. They currently include clips on preparation of inoculum, inoculation, application of disks and incubation, reading of zones and guidance on breakpoint tables.

ESCMID's AMR initiatives

A. van der Zande (Director General RIVM), Z. Jakab (Regional Director WHO Europe), G. Kahlmeter (ESCMID President) sign memorandum for CAESAR project in September 2012

ESGAP – The ESCMID Study Group for Antibiotic Policies has conducted the project New Life for Old Antibiotics, jointly with ESCMID’s PK/PD of Anti-Infectives Study Group (EPASG) , and have presented the results at an ESCMID Conference to this topic resulting in several publications (Link to conference website for all information). A dedicated website set up by these two groups hosts more background information on the same topic.

ESGARS – The ESCMID Study Group for Antimicrobial Resistance Surveillance is currently running the CAESAR project together with WHO-Europe and RIVM (NL) to set up an antimicrobial resistance surveillance system in European countries not formally taking part in EARS-Net.

ESGNI – The ESCMID Study Group for Nosocomial Infections is currently involved in the ECDC project TRICE for training in infection prevention and control to ultimately curb spread of antimicrobial resistance. On the same topic, the group runs an annual training course.

ESCMID was partner in "Translational Research on Combating Antimicrobial Resistance" (TROCAR), which was a research project funded by the Seventh Framework Programme of the European Commission (2009-2012). The driving concept of TROCAR was to investigate the fundamentals of the epidemiology of new highly virulent multiresistant strains.

ESCMID was partner in "Genomics to Combat Resistance against Antibiotics in Community-acquired LRTI in Europe" (GRACE), which was a network of excellence devoted to tackling the increasing problem of resistance to antibiotics when dealing with lower respiratory tract infections, such as bronchitis or pneumonia. This research project was funded by the Sixth Framework Programme of the European Commission (2006-2011).

The European Committee on Antimicrobial Susceptibility Testing, jointly organized by ESCMID and ECDC, is responsible for determining breakpoints for bacteria and fungi for existing and new antimicrobial agents.

The European Committee on Infection Control (EUCIC) aims to strengthen infection control and preventive measures in European countries to reduce the burden of healthcare-associated infections (HAIs).

ESCMID organizes the top congress in clinical microbiology, infectious disease and infection control. ECCMID provides 12,000 specialists with a platform for knowledge exchange, coordination of initiatives and building, maintaining and expanding networks in the fight against antimicrobial resistance.