Individualized Medicine in Infectious Diseases: a Practical Approach, ESCMID Postgraduate Education Course

3 - 4 June 2016, Tübingen, Germany

  • ESCMID Parity Commission
  • ESCMID PK/PD of Anti-Infectives Study Group (EPASG)
  • ESCMID Study Group for Antibiotic Policies (ESGAP)
Course Coordinators
  • Angela Huttner, Geneva, Switzerland
  • Evelina Tacconelli, Tübingen, Germany
Course Objectives

Participants of this course will:

  • Understand the pharmacokinetic and epidemiologic heterogeneity in patient populations, including those traditionally excluded from clinical studies such as the critically ill, the elderly, those with renal insufficiency, the obese, and female patients
  • Understand the clinical implications of variations in local epidemiology, microbiota, and regional perceptions regarding antimicrobial use
  • Explore the clinical evidence for recommended durations of antimicrobial therapy
  • Identify existing tools for individualized diagnostics and therapy, such as:
    – Point-of-care diagnostics
    – Therapeutic drug monitoring of antimicrobials
    – Web-based software for individualized dosing with Bayesian adaptive feedback
    – Non-antibiotic approaches to therapy, such as delayed prescription, vaccination and antibody therapy
  • Explore the cognitive biases that can impede accurate diagnosis in various populations
  • Explore the ethical dilemmas in antimicrobial decision-making (the individual versus society)
Course Venue

Universitätsklinikum Tübingen
Otfried-Müller-Strasse 12
72076 Tübingen

Target Audience

30 – 60 microbiologists, clinical infectious disease specialists, or other healthcare professionals with interest in individualized medicine in infectious diseases.

Contact Person (Scientific Programme)

Angela Huttner
Geneva University Hospitals
Rue Gabrielle-Perret-Gentil 4
1205 Geneva

Phone +41 79 553 33 96
Fax +41 223 724 097

Administrative Secretariat

Gabriele Dold-Ghadar
Abteilung Innere Medizin I
Gebäude 560, Raum 929, Ebene 03
Otfried-Müller-Str. 10
72076 Tübingen

Phone +49 707 129 836 85
Fax +49 070 712 51 15

Course Programme


Presentations are availabe in the ESCMID Online Lecture Library.

Friday, 3 June 2016

08:45 Registration
09:00 Introduction: “Patients like mine” – problems & solutions. Angela Huttner

Session 1
Individualized epidemiology
09:10 Know your local epidemiology and the tools for keeping tabs on it. Dominique Monnet
09:40 Know your patient’s risks I: sex-based and other differences in infectious disease pathogenesis and immunity. Marylyn Addo
10:10 Know your patient’s risks II: learning your patient’s pharmacokinetics – as much as possible. William Hope
10:40 Coffee break

Session 2
A diagnosis in time
11:00 Rapid diagnostic testing in infectious diseases: where are we now?
Surbhi Malothra-Kumar

11:30 Genetic testing: can it make an infectious disease diagnosis? Pierre-Yves Bochud
12:00 Cognitive bias and accurate diagnosis: what are our stumbling blocks? Mical Paul
12:30 Lunch

Session 3
A pound of prevention – tailored to your patient

13:30 Alternate strategies in the age of resistance: delayed prescription, vaccines, antibodies. Angela Huttner
14:00 Individualized infection control measures: are they possible? Andreas Widmer
14:30 Coffee break

Workshop 1
15:00 Interactive session: proposals for research projects on individualized therapy in infectious diseases to be discussed with experts (I)

Saturday, 4 June 2016

Session 1
Towards individualized therapy of infections
09:00 Special populations: the immunosuppressed, the critically ill, and others.
Andrew Ullman
09:30 Durations of therapy: from arbitrary numbers to biomarker- and algorithm-based guidance. Werner Albrich
10:00 Individualized PK/PD approaches to antimicrobial therapy. William Hope
10:30 Coffee break
11:00 The impact of antimicrobial resistance on clinical daily prescribing. Evelina Tacconelli

Session 2
The “swampy lowlands”: where guidelines meet the complexity of today’s populations

11:30 “Omics”: myths and real-life applications. Silke Peter
12:00 Guidelines and evidence in infectious diseases: where do they come from and how applicable are they? Benedikt Huttner
13:00 Lunch break

Session 3
Improving care for your patient and future ones

14:00 Will individualization of care diminish the evidence base? Marc Bonten
14:30 The individual versus society: ethical dilemmas in antimicrobial decision-making. Leonard Leibovici
15:00 Coffee break

Workshop 2
15:30 Interactive session: proposals for research projects on individualized therapy in infectious diseases to be discussed with experts (II)
17:00 Concluding remarks

Faculty Members
  • Marylyn Addo, Hamburg, Germany
  • Pierre-Yves Bochud, Lausanne, Switzerland
  • Werner Albrich, Basel, Switzerland
  • Marc Bonten, Utrecht, Netherlands
  • William Hope, Liverpool, United Kingdom
  • Angela Huttner, Geneva, Switzerland
  • Benedikt Huttner, Geneva, Switzerland
  • Leonard Leibovici, Tel Aviv, Israel
  • Surbhi Malothra-Kumar, Antwerp, Belgium
  • Dominique Monnet, Solna, Sweden
  • Mical Paul, Haifa, Israel
  • Silke Peter, Tübingen, Germany
  • Evelina Tacconelli, Tübingen, Germany
  • Andrew Ullman, Würzburg, Germany
  • Andreas Widmer, Basel, Switzerland

CME Accreditation
The event has been granted with 12 CME points by EACCME.