Research & Projects

ESCMID Panorama

ESCMID PK/PD of Anti-Infectives Study Group - EPASG

News & Activities

  • Saturday, 10 May 2014
    8.45 - 10.45 (Hall C)
    Educational Workshop 02: Basic concepts of pharmacokinetics and pharmacodynamics.
    16.30 - 18.30 (Hall C)
    EPASG Symposium: The Good, the Bad and the Ugly: recently approved and developmental anti-bacterials.
  • Sunday, 11 May 2014
    18.15 - 19.15 (Room 131)
    EPASG Business Meeting: All interested persons are cordially invited to join the meeting and plan future Study Group activities.
  • Monday, 12 May 2014
    7.45 - 8.45 (Hall H)
    EPASG Meet-the-Expert Session: Altered drug disposition in the elderly, organised jointly with the ESCMID Study Group for Infections in the Elderly (ESGIE).
  • Tuesday, 13 May 2014
    9.00 - 11.00 (Hall H)
    EPASG Symposium: PK/PD - the merits of models and measurement.

For more details, please check the ECCMID programme.

ECCMID programme

This comprehensive resource on old antibiotics provides information on

  • Current knowledge of old revived antibiotics regarding PK/PD, dosing, emergence of resistance
  • Knowledge gaps and current research activities
  • Regulatory aspects and inventory of outdated dosing regimens, analysis of Summary of Product Characteristics (SPCs)
  • Regularly updated new knowledge, especially from the FP7 AIDA project on "Old antibiotics for the future"

EPASG @ ECCMID 2014 in Barcelona, Spain

  • Educational Workshop: Basic concepts of pharmacokinetics and pharmacodynamics
  • Symposium: PK/PD - the merits of models and measurement
  • Symposium: The Good, the Bad and the Ugly: recently approved and developmental antibacterials
  • Meet-the-Expert Session (jointly organised with ESGIE): Altered drug disposition in the elderly
  • EPASG Business Meeting: All interested persons are cordially invited to join the meeting and plan future EPASG activities and collaborations.

For more details, please check the ECCMID programme. Exact dates, times and rooms will be added in the course of February.

ECCMID programme

  • Saturday, 27 April 2013
    08.45 - 10.45 (Hall 4/5)
    EPASG Educational Workshop 3: Translational PK/PD - from bench to bedside
    08.45 - 13.00 (Hall 2)
    Educational Workshop 1: Antimicrobial susceptibility testing with EUCAST breakpoints and methods - What is new in 2013: update on EUCAST breakpoints
    13.30 - 15.30 (Hall D)
    EPASG Symposium (jointly organised with ESGICH): Pharmacokinetic and pharmacodynamic issues for antimicrobial therapy in patients with cancer
  • Sunday, 28 April 2013
    18.15-19.15 (Salon 22)
    EPASG Business Meeting: All interested persons are cordially invited to join the meeting and plan future EPASG activities and collaborations.
  • Monday, 29 April 2013
    07.45 - 08.45 (Hall A)
    Meet-the-Expert Session: Pharmacodynamics for dummies
  • Tuesday, 30 April 2013
    07.45 - 08.45 (Hall E)
    Meet-the-Expert Session: Dosing challenges in the ICU
    09.00 - 11.00 (Hall D)
    EPASG Symposium (jointly organised with ESGVH): The revolving alphabet soup of hepatitis viral infections
  • European Network Corner: Presenting EPASG and the EU-funded project AIDA

For more details, please check the ECCMID programme.

ECCMID programme

Future projects

So far two major projects are planned for 2013 and hopefully suggestions for more activities will be discussed during our business meeting at ECCMID in Berlin (see below for details).

  • New Life for Old Antibiotics: This project will create the first inventory of dosing regimens of old antibiotics in European countries that need an update of their dosing schedules and indication list to preserve their efficacy.
  • ESCMID and EPASG will co-organise the first Conference “Re-development of Old Antibiotics” in October 2014 in Vienna, Austria. The first announcement will be available at ECCMID in Berlin.

EU Projects

  • Many of the founding members, along with other active Study Group members are collaborating in the FP7 funded Project AIDA: “Preserving old antibiotics for the future: assessment of clinical efficacy by a pharmacokinetic/pharmacodynamic approach to optimize effectiveness and reduce resistance for off-patent antibiotics”. As Project AIDA progresses, we will post additional background information and project results to our project website (www.aida-project.eu).
  • A similar team of active Study Group members under the leadership of J. Mouton prepared a proposal in response to the FP7-HEALTH-2013-INNOVATION-1 call “Stratified approaches to antibacterial and/or antifungal treatment.”

Main educational activities in 2012/2013

  • The hands-on Postgraduate Education Course “A statistical approach to PK-PD analysis in practice”, organised by EPASG, 8 - 11 October 2012 in Athens, Greece, was highly appreciated.
  • EPASG co-organised the Postgraduate Technical Workshop “Antimicrobial susceptibility testing and surveillance: from laboratory to clinic. A EUCAST, ESGARS and EPASG perspective”, 25 - 28 September 2012 in Madrid, Spain. All materials of this workshop are available in the Online Lecture Library.
  • The Postgraduate Education Course: “Antimicrobial Stewardship in Hospitals”, organised by ESGAP will take place on 25 - 26 April 2013 in Zeuthen near Berlin, Germany.
  • 31 March, 8.45-10.45
    Educational Workshop EW02 "Optimising treatment based on a pharmacodynamic approach: an interactive workshop using clinical cases"
  • 31 March, 16.30-18.30
    2-hour Symposium "Update in drug development"
  • 1 April, 18.15-19.15 (Meeting Room 11)
    EPASG Business Meeting
    All interested persons are cordially invited to join the meeting and plan future EPASG activities.

For more details, please check the ECCMID programme.

ECCMID programme

EPASG @ ECCMID/ICC in Milan, IT, May 2011

  • 8 May, 7.45-8.45
    Meet-the-Expert Session "PK/PD for non-experts"
  • 8 May, 12.30-13.30 (Press Conference Room)
    EPASG Business Meeting
    All interested persons are cordially invited to join the meeting and plan future EPASG activities.
  • 10 May, 9.00-11.00
    Symposium "Bridging the gap of innovation - what we all could do"

For more details, please check the ECCMID/ICC programme.

ECCMID/ICC programme

 

FP7-HEALTH.2011.2.3.1-1 Investigator-driven clinical trials of off-patent antibiotics.
Topic:  Defining optimal treatment regimens (including drug choice, combinations, dosing, duration of therapy, PK/PD, individualisation) of off-patent antimicrobial agents for therapy of difficult-to-treat infections caused by multidrug resistant bacterial pathogens in terms of maximising clinical benefit and minimizing selection of resistance.

The application for this two-stage grant has been accepted by the European Commission.

We will proceed with our planning for 3 randomised clinical trials, in vitro, animal studies, as well as dissemination and educational activities

Project leader:

First PK/PD Symposium in Vienna, AT

  • Symposium after the ECCMID 2010 in Vienna: Special PK/PD topics in collaboration with ISAP, 13 April 2010, 14.00-17.30
    Programme
Last update: 25 April 2014

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