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5 March 2019

Dear colleagues,

Please find below the latest edition of ESCMID Weekly News.

With kind regards,

ESCMID Executive Office.


ECCMID 2019 – Programme sneak peak

ECCMID is approaching soon in Amsterdam!

Have a sneak peak at what’s new this ECCMID with an exclusive video interview with ECCMID Programme Committee member Mary Horgan.

Registrations are available at a reduced rate for ESCMID members on the official website.

Make sure you use our official website to book your hotels to get the best rates.

› Read more

Pre-ECCMID Machine Learning for Microbiology Workshop

Complement your ECCMID 2019 experience with the 'Machine Learning for Clinical Microbiology' the day before ECCMID in Amsterdam.
This workshop is happening on Friday, 12 April. Sign up using the ECCMID registration portal!

Limited places are available, the full day is only €100!

› Read more

ECCMID Live is now active!

Keep up to date with the latest version of the ECCMID programme with ECCMID Live, the official interactive session guide!

Log in to plan your ECCMID journey and fill in your personal timetable.

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#myECCMID – Share your ECCMID story

Be a part of the great ECCMID community and share your ECCMID story with us!

Share your ECCMID highlights, great moments and experiences. Just log in to the congress portal and send us your story and photo.

1.    Log in and choose #MyECCMID
2.    Complete your personal data
3.    Enter text and upload a photo
4.    Submit
The #MyECCMID stories will be broadcasted during the 29th European Congress of Clinical Microbiology & Infectious Diseases in the public area.

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IMMEM XII abstract submission is open

Submissions for abstracts for the 12th International Meeting on Microbial Epidemiological Markers (IMMEM XII), to be held in Dubrovnik, Croatia, from 18-21 September 2019.

Abstract submission for paper poster presentations at IMMEM are now open on the course website, and will close on April 30 23:59 CET.

Conference registrations will open soon also!

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CMI Highlight: Prevalence of antimicrobial resistance genes in Bacteroides spp. and Prevotella spp. Dutch clinical isolates

Veloo et al., studied the prevalence of resistance genes in two important anaerobic genera, Bacteroides and Prevotella, was assessed by applying PCR specifically directed to genes of interest.

A total of 101 Bacteroides spp. and 99 Prevotella spp. human clinical isolates were identified using MALDI-TOF MS. The presence of the resistance genes cfxA, cepA, cfiA, tetQ, ermF, and nim, was evaluated. The prevalence of resistance genes was compared to phenotypic resistance to amoxicillin, clindamycin, meropenem and metronidazole.

Even though the majority of the Bacteroides isolates (92.1%) showed resistance towards amoxicillin, only 52/101 of the isolates harbored one of the resistance genes, accounting for this resistance. Within the genus Prevotella the presence of cfxA (50/99) almost perfectly matches the amoxicillin resistance (48/99). No difference in prevalence of the ermF gene (16/101 and 9/99) and clindamycin resistance (16/101 and 10/99) was observed within Bacteroides and Prevotella, respectively. Two isolates of Prevotella were resistant for metronidazole. One harbored the nim gene. One metronidazole susceptible isolate of Bacteroides harbored a nim gene. Within the Bacteroides and Prevotella genera, 6/101 strains and 5/99 isolates harbored three different resistance genes, respectively, among them tetQ. TetQ is often located on a conjugative transposon, increasing the chance of horizontal gene transfer between isolates.

The author unraveled an unknown mechanism in Bacteroides non-fragilis isolates causes resistance to beta-lactam antibiotics.

Veloo et al. Showed that the prevalence of the tetQ gene among Prevotella is increasing and the existence of isolates harboring three resistance genes which is a worrying development.

› Read more
ESCMID Executive Office
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The ESCMID Newsletter is issued on behalf of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) by the ESCMID Executive Office. It contains announcements of ESCMID-related matters and other information of interest to professionals in the infection field.

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