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22 August 2017

Dear colleagues,

ESCMID is looking to fill the position of Medical Guidelines Director who will oversee ESCMID’s medical guidelines portfolio, including the development and update of medical guidelines, reporting directly to ESCMID’s Executive Committee. A full description of the responsibilities, qualifications and requirements can be found here.

The Executive Office has two new job openings based in Basel: a junior accountant/administrator and a junior project manager events. You find more information on the ESCMID website.

Over the summer some new papers, which will be included in an ESCMID Vaccine supplement entitled Progress in Vaccines have been published online. The special issue, managed by the guest editors Mario Poljak, Susanna Esposito and Litjen Tan, includes papers on presentations at ECCMID 2016 in Amsterdam as well as manuscripts complementing the topic.


EUCIC publishes review on methodology of AMR and HAI surveillance

Members of EPI-NET, COMBACTE-NET and the EUCIC group for SUSPIRE published a systematic review, which evaluated healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) indicators of 56 surveillance systems in 20 countries across Europe. Of these surveillance systems, 33 (58.9%) targeted HAIs, 45 (80.3%) AMR and 22 targeted both. The most frequent indicator of AMR was the proportion of resistant isolates (27/34 providing information; 79.42%); incidence rates were included in 18 (52.9%) systems. For HAIs in ICUs, 22 (100%) systems included data on central line-associated bloodstream infections, 19 (86.3%) included information on ventilator-associated pneumonia and catheter-associated urinary tract infections. Incidence density was the most frequent indicator in these types of infections. Regarding surgical site infections, the most frequent procedures included were hip prosthesis, colon surgery and caesarean section (21/22 systems; 95.5% of the systems). The authors conclude that publicly available information about the methods and indicators of surveillance systems is still frequently lacking and that there is a wide heterogeneity in procedures and indicators reported.

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Register now for the ESCMID omics course in Grenoble, 6 – 8 September

The course Omics of Host and Pathogens During Infections offers high-quality interdisciplinary training on the technological and bioinformatic skills necessary for the use of state-of-the-art omic technology tools to rapidly translate disease research into improved clinical healthcare. The course objective is to provide PhD students, postdocs and early stage clinicians who are involved in laboratory and clinical work with an up-to-date overview of the available technologies and approaches. It will address research topics, diagnostic development, and most importantly will cover the essential steps in standardizing and benchmarking next-generation genomic technologies for diagnostic applications.

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CMI highlight: Review of bloodstream infection in cirrhotic patients

Bartoletti et al. investigated the epidemiology of bloodstream infections (BSI), predictors of 30-day mortality and risk factors for antibiotic resistance (multi-drug resistant organisms, [MDRO]) in patients with liver cirrhosis. BSI were caused by Gram-negative bacteria (53%), Gram-positive bacteria (47%) and Candida spp. (7%). Cox-regression analysis revealed that the 30-day mortality rate (25%) associated independently with delayed antibiotic treatment, inadequate empirical therapy and the CLIF-SOAF score. Independent risk factors (31% of BSIs) included previous antimicrobial exposure and previous invasive procedures. Spontaneous bacterial peritonitis as BSI source was associated with lower odds of MDRO infections. The authors urge to improve prevention and treatment strategies for MDRO in liver cirrhosis patients, as such infections account for nearly one third of all BSI in these patients and often result in delayed or inadequate empirical antimicrobial therapy and increased mortality rates.

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Other events in the network on infectious diseases, antibiotics, HIV

The first Singapore International Infectious Disease Conference from 24 to 26 August 2017 in Singapore will focus on emerging infections and outbreaks in addition to general infectious diseases such as HIV, tuberculosis, malaria, antimicrobial resistance, fungal infections, dengue, Zika, MERS/SARS/pneumonia.

The DRIVE-AB Final Conference, “Revitalizing the Antibiotic Pipeline” from 5 – 6 September 2017 in Brussels, Belgium, will bring together high-level policy makers, regulatory and public health experts, economists and representatives of pharmaceutical companies, the medical community and civil society to discuss DRIVE-AB results and recommendations and to suggest solutions for their implementation around the globe.

The 2nd HIV Cure and Reservoir Symposium from 11 - 12 September 2017 in Ghent, Belgium, will comprehensively summarize the state of the art in HIV cure strategies and diagnostic tools to monitor therapeutic interventions.

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The ESCMID Newsletter is issued on behalf of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) by the ESCMID Executive Office. It contains announcements of ESCMID-related matters and other information of interest to professionals in the infection field.

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