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14 August 2018

Dear colleagues,

Please find below the latest edition of ESCMID Weekly News.

With kind regards,

ESCMID Executive Office.


EITaf News: Call for doctors interested in the control of the new Ebola outbreak in the Congo

GOARN, the WHO Global Outbreak Alert and Response Network, is requesting qualified volunteers in specified fields for a minimum of 6 weeks to assist in the outbreak response to the newly confirmed Ebola outbreak.

If you are interested and available, please contact EITaF for additional information and please send us an updated CV, and dates of availability and we will forward your information to the WHO.

Fluency in spoken and written French is a necessity for deployment to affected areas.

› Read more

ESCMID Postgraduate Education Course - Seville, Spain

Don’t miss out on the opportunity to participate in the ESCMID Postgraduate Course ‘Better Methods for Clinical Studies in Infectious Diseases and Clinical Microbiology: a Hands-on Workshop’, to be held in November in Seville, Spain.

The course has been granted 16 European CME credits (ECMEC®s) by the European Accreditation Council for Continuing Medical Education (EACCME®).

Attendance grant applications close this Friday, 17 August.

› Read more

ESGAP publishes the results of the LEASH survey, the LEgal framework for Antimicrobial Stewardship in Hospitals

Beovic et al publish the results of a cross-sectional international survey inquiring experts in 32 European countries (plus Israel and Turkey) on the legal framework and components required by legislation or regulators in their countries to implement AMS activities. Responses from 25 countries and two regions (in countries with federal health administration) revealed that laws regulating AMS existed in 7 countries and in one region, whereas other regulations existed in 13 countries and in one region; no regulations existed in five countries and in one region. Funding for AMS activities in hospitals was available in five countries and in one region. Mandatory AMS structures and activities existed in 8 countries and in one region. However, in 10/27 cases, such activities were not fully carried out. Overall, the survey showed heterogeneous legal frameworks for AMS in hospitals across countries, which could lead to critical situations in countries with poor control of antimicrobial use and resistance. The authors emphasize the recent international initiatives calling on policy-makers to address the threat of AMR.

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CMI highlight: Carriage of the staphylococcal surface protein encoding sasX/sesI in India and Europe

De Backer et al studied the spread of sasX as well as the population structure of MRSA in samples from tertiary care patients in Europe (n=119) and India (n=9). In India, SasX and sesI (an S. epidermidis sasX homologue) were detected in five of the nine MRSA belonging to ST239 and other ST types of CC8, while in Europe, sasX was restricted to two ST239 strains. The intact sasX and sesI carrier φSPβ-like prophages were ∼80 kb and ∼118 kb, which integrated into the yeeE gene. Furthermore, ‘novel’ ST239 clades in India and Serbia were discovered, which showed significant differences in base substitution frequencies (0.130 and 0.007, respectively, Tamura-Nei model; P<0.05). Together these data highlight the dissemination of sasX to non-ST239 STs of CC8. The detection of the S. epidermidis-associated sesI in MRSA provided unquestionable evidence of a transfer taking place between the two species. Stark differences in evolutionary rates between the identified novel Indian and Serbian ST239 clades might be due to inherent clade characteristics or be influenced by other environmental differences such as antibiotic use.

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ESGNI publication: Variability in contact precautions to control the nosocomial spread of multi-drug resistant organisms in the endemic setting: a multinational cross-sectional survey.

Definitions and practices concerning use of contact precautions and isolation to avoid the spread of gram-positive and gram-negative multidrug-resistant organisms (MDRO) are not fully standardized. Gysin et al. published the results of an outstanding on-site survey conducted during the European Congress on Clinical Microbiology and Infectious Diseases (ECCMID) 2014 with the aim to evaluate specific details on contact precaution and implementation barriers.

› Read more
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