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10 April 2018

Dear colleagues,

Finance and HR Manager Milena Griffiths, who had joined ESCMID three years ago, left the society yesterday. We thank Milena warmly for all her commitment and her hard work particularly also in the past year. Next week Science Manager Henri Saenz will also leave ESCMID. Henri has been with the society for almost 12 years supporting the study groups, organising the research grants and supporting the ECCMID Programme Director with the scientific programme. He will be sorely missed. We wish both all the best in their future careers. We warmly welcome a new manager in the Office, Daniele Roppolo, a molecular biologist who will take over many of Henri’s task.

Your ESCMID communications editors


ECCMID is less than two weeks away!

Highlights include keynote lectures, educational events and additional new formats. The scientific programme is available now for download. The keynotes on Monday for example include George Daikos’ lecture on extensively-drug resistant (XDR) gram-negative organisms, which cause serious infections associated with increased mortality in many hospitalized patients. Daikos will provide an overview of the experimental data, the accumulated clinical experience and the upcoming new agents with potential activity against these devastating pathogens. Also on Monday Nathalie Questembert-Balaban will discuss phenotypic variability and the evolution of antibiotic tolerance and persistence, which may lead to infection relapse once antibiotic treatment is stopped, and Christian Drosten will discuss SARS, MERS and other coronaviruses to come. He will for example show how the emergence of novel coronaviral diseases has repeatedly involved drastic changes of tissue tropism, involving fundamental changes of disease pattern and transmissibility.

Like in the previous three years, ECCMID will organize a Pipeline Corner where smaller pharmaceutical and diagnostic companies give an overview over the products in development. In addition, there will be a new format, the Open Forum presentations, which feature expert discussions on various topics including sepsis (position paper mentioned below) and antimicrobial resistance.

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Places at TAE Day on 21 April at 13:15 are booking up fast so sign up now!

To ensure you can speak to your chosen CM or ID expert, sign up here now. This is a popular session which gives younger professionals the chance to talk to experts in an informal setting. The TAE Award will also be presented during the session and you will hear from the Young Investigator awardees. The deadline for registration is 19 April.

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CMI highlight: ESGCIP, ESGBIS, position paper on sepsis

The ESCMID study groups for infections in critically ill patients and bloodstream infections and sepsis published a position paper on sepsis. The researchers summarized the current evidence on precision medicine in sepsis focusing on the interplay between therapies, pathogens and the host and emphasising translation from theory to clinical practice. A secondary objective was to develop recommendations on the management and priorities for further research. They also discuss microbiologic diagnostic approaches including blood cultures (BCs) and rapid diagnostic tests (RDTs) as well as targeted antibiotic treatment. Other topics include the disruption of the host immune system and the use of biomarkers in sepsis management, patient stratification and future clinical trial design. Lastly, personalized antibiotic treatment and stewardship are addressed. The authors provide a road map for recommendations and future perspectives to establish precision medicine in sepsis. RDTs and identifying drug-response phenotypes are two of the main challenges. The next step will be the implementation of precision medicine to sepsis management based on theranostic methodology. This highly individualized approach will be essential for the design of novel clinical trials and improvement of care pathways, the researchers conclude. The lead researchers will present their sepsis paper in an Open Forum discussion on 24 April at noon during ECCMID in Madrid.

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ESCMID Summer School in Paris from 1 – 7 July 2018

During the one-week course postgraduate and continuing medical education participants may enjoy excellent lectures by renowned experts in the field and network with peers in a relaxed setting. The programme covers a broad range of topics in clinical microbiology and infectious diseases and will interest young medical doctors at the end of their specialty training as well as biologists, pharmacists, PhD students and postdoctoral fellows working in the infection field.

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The ESCMID Newsletter is issued on behalf of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) by the ESCMID Executive Office. It contains announcements of ESCMID-related matters and other information of interest to professionals in the infection field.

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