We are very happy to continue this tradition and to again bring together outstanding scientists, leading government officials, and high-level representatives from civil society and the health industry. A core and essential function of the World Health Summit is to establish a forum to discuss the most pressing challenges that medicine and global health will face over the next decade and beyond. The Charité-Universitätsmedizin Berlin is very proud to be the host of this initiative, coinciding with the 300th anniversary of this institution.