Antimicrobial Susceptibility Testing and Surveillance: from Laboratory to Clinic - the EUCAST and ESGARS Perspective, ESCMID Postgraduate Education Course

27 - 30 September 2010, Madrid, Spain

Organizers

Jointly organized by the European Committee on Antimicrobial Susceptibility Testing (EUCAST) and the ESCMID Study Group for Antimicrobial Resistance Surveillance (ESGARS).

Course Coordinators

for EUCAST

Derek Brown, Peterborough, UK
Rafael Cantón, Madrid, ES
Gunnar Kahlmeter, Vaxjo, SE

for ESGARS

Giuseppe Cornaglia, Verona, IT
Luis Martínez-Martínez, Santander, ES
Gian Maria Rossolini, Siena, IT

Course Objectives

Explain the current process of EUCAST breakpoint definition, understand the rationale for EUCAST breakpoints and explain implementation of EUCAST breakpoints
Perform antimicrobial susceptibility testing by dilution, diffusion and automatic techniques, with a EUCAST perspective and explain differences from the CLSI approach
Understand the application of EUCAST expert rules for antimicrobial susceptibility testing
Explain antimicrobial surveillance systems (public versus private) and benefits for establishment of antimicrobial guidelines and the design of antibiotic policies
Understand the importance of breakpoints in antimicrobial resistance surveillance systems

Course Venue

Microbiology Department, School of Pharmacy
Complutense University
Madrid, Spain

Target Audience

30-35 clinical microbiologists with an interest in antimicrobial susceptibility testing and surveillance. Representatives from National Antimicrobial Committees will have preference over other applicants for participation in this PGEC.

Registration Fee

EUR 500 for ESCMID members

EUR 750 for all others

The fee includes the laboratory materials and protocols, lunch at the university and social events.

Attendance Grants

ESCMID provides a number of attendance grants for young attendees (up to 40 years) covering the registration fee, but no travel or accommodation costs. Please submit your application until 15 July 2010 online on this website (see right column). If there are more applicants than available grants, preference will be given to ESCMID members. Applicants will be informed about their acceptance by 31 July 2010.

Please note that attendance grant application does not include registration for the course. Please register separately with the form supplied on the right.

Contact Persons (educational programme)

Rafael Canton, Madrid, ES
Rafael Canton

Luis Martinez-Martinez, Santander, ES
Luis Martinez-Martinez

Administrative Secretariat

Ana Moreno-Bofarull
Servicio de Microbiología
Hospital Universitario Ramón y Cajal
Carretera de Colmenar, Km 9, 100
28034 Madrid, Spain

Phone +34 913 36 88 32
Fax +34 913 36 88 09

A. Moreno-Bofarull

Course Programme

Lectures

Monday , 27 September 2010
15:00 – 15:30 Arrival. Coffe.
15:30 – 15:40 Presentation of the course.
15:40 – 16:20 European (EUCAST) breakpoint setting and harmonization. Gunnar Kahlmeter
16:20 – 17:00 Breakpoints. EUCAST or CLSI? Derek Brown
17:00 – 17:40 Importance of PK/PD data in the process of setting breakpoints. Johan W. Mouton
17.40 – 18:10 Anaerobes: breakpoints and surveillance. Arne Rodloff
19:00 – Reception dinner

Thuesday, 28 September 2010
9:00 – 9:40 Antimicrobial susceptibility testing: diffusion methods. Gunnar Kahlmeter
9:40 – 10:20 Antimicrobial susceptibility testing: dilution methods. Luis Martínez-Martínez
10:20 – 10:45 Coffe break
10:45 – 11:25 Quality assurance of susceptibility testing. Derek Brown
11:25 – 12:05 Phenotypic methods for detection of resistance mechanisms. Christian Giske
12:05 – 12:45 EUCAST expert rules. Christian Giske
12:45 – 13:45 Lunch

13:45 – 17:45 Laboratory sessions

Wednesday, 29 September 2010
9:00 – 9:40 Antimicrobial susceptibility testing: automatic systems. Rafael Cantón
9:40 – 10:20 Emerging problems in susceptibility testing of Gram-negatives. Gian Maria Rossolini
10:20 – 10:45 Coffee break
10:45 – 11:25 Emerging problems in susceptibility testing of Gram-positives.Rafael Cantón
11:25 – 12:05 Surveillance of Gram-negatives with low-level resistance mechanisms. Álvaro Pascual
12:05 – 12:45 Surveillance of gram-positives with low-level resistance mechanism. Emmanuelle Cambau
12:45 – 13:45 Lunch

13:45 – 17:45 Laboratory session

Thursday, 30 September 2010
9:00 – 9:40 Genotypic methods for detection of resistance. Luis Martinez-Martinez
9:40 – 10:20 Surveillance. Public versus private. Giuseppe Cornaglia
10:20 – 10:45 Coffee break

10:45 – 13:30 Laboratory session

13:30 Closing and farewell lunch

Practical, Laboratory Sessions

Tuseday and Wednesday 13:45-17:45
Thursday 10:45 - 13:30

International Standards Organization (ISO) microdilution and other dilution techniques
Diffusion techniques (disk diffusion and gradient strips)
Automated systems for antimicrobial susceptibility testing
Tests for specific resistance mechanisms (ESBLs, AmpC, carbapenemases, hVISA, etc)
Epidemiolgical surveillance computer programmes
Computer expert programmes

Course Faculty

Lecturers

Derek Brown, Peterborough, UK
Emmanuelle Cambau, Paris, FR
Rafael Cantón, Madrid, ES
Giuseppe Cornaglia, Verona, IT
Christian Giske, Stockholm, SE
Gunnar Kahlmeter, Vaxjo, SE
Luis Martínez-Martínez, Santander, ES
Johan W. Mouton, Nijmegen, NL
Álvaro Pascual, Seville, ES
Arne Rodloff, Leipzig, DE
Gian Maria Rossolini, Siena, IT